TOP

From reads  to clinical reports....
we have you covered.

  • Solution designed to support clinical lab workflows.
  • Reduces clinical interpretation and reporting time from days to a few hours.
  • Based on first-hand experience interpreting over a 100 cases in our clinical genomics lab.

If you are interested in participating in our Early Access Program,

Literature
Curation
Bioinformatic
Data Curation

We provide around the-clock support Monday to Friday. Please call/email us and our support team will get back to you on priority.

Email: support@strandomics.com
Phone (USA): 1-800-516-5181
Phone (Worldwide): +1-650-288-4559

StrandOmics is HIPAA Compliant:
View report

Clinicians and Patients

We designed Strandomics after extensive interactions with practicing clinicans, patients, clinical interpreters, genetic counselors, and medical geneticists. Strandomics has now been used for analysis and reporting on many many cases, drawn from a growing list of more than 50 hospitals, including world renowned specialist centers in cancer, cardiology and ophthalmology as well as leading community hospitals (a few examples below). Several leading centers in the US are now using Strandomics as part of the Early Access Program.

Sequencing

Strand Centers, our clinical testing arm has used our platform in more than a hundred cases, and has touched many lives with the platform.

A few examples:
  1. A family with several individuals affected by loss of central vision in their 30s. We found pathogenic compound heterozygous variants in the ABCA4 gene, confirming diagnosis of Stargardt disease. The younger family members were found to be missing at least one variant, giving them good prognosis.
    [ Download pdf ]
  2. A family who had lost two children early in life to respiratory distress. We found a novel missense variant in the FLNA gene. The family's third pregnancy was checked and found to have the same genotype as the mother, making the foetus unlikely to be affected. This little girl was born 6 months ago and is doing well.
    [ Download pdf ]
  3. Two siblings with a serious heart condition. We found a likely pathogenic splice site variant in the DSP gene. Other siblings now have a tool to know whether they are at risk or not.
    [ Download pdf ]
  4. Two children with extreme sun sensitivity and high risk of skin cancer. We found a likely pathogenic start lost variant in the ERCC5 gene, with the next start predicted to cause a frameshift and premature truncation.
    The family now has a tool to plan future children.

Variant Detection

Widely adopted Algorithms for Alignment and Variant Calling

Our variant detection algorithms have been used extensively in clinical applications.

For instance, click here to see how Wafergen Biosystem used our variant identification algorithms to validate their clinical assays.

And click here to see how the Sanford-Burnham institute used our variant identification algorithms to find the cause of a very rare disorder called CHIME disease.

And click here to see how a team of scientists from various Japanese medical schools used our variant detection algorithms to find a novel gene candidate for Andersen-Tawil syndrome.

And click here to see how the New York City Office of Chief Medical Examiner used our variant detection algorithms to study the cause of sudden unexplained death in a cohort of 274 individuals.

White papers that benchmarks our Alignment and Variant Calling algorithms with leading open source algorithms and show how our algorithms provide greater accuracy are available.

Comprehensive Variant Annotation

  • Is the variant in a conserved location?
  • Are there other known variants near the case variant?
  • What is the technical quality of this variant?
  • What are the Phenotypes associated with this disease?
  • Which diseases are associated with this gene?
  • What is the effect of the variant on a specific transcript of the gene?
All these and more... supported by a team of scientists curating the latest literature and incorporating public variant databases.

Effortless Interpretation and Reporting

The following statistic gathered in over a hundred cases says it all. When a clinically significant pathogenic, likely pathogenic or strong VUS exists, we usually find it in under 5min using our simple point-and-click interface.

If you'd like to scale up this process, we support capture of comments and role-based access to enable reviews. And we support systematic SOPs to ensure consistency of comments. And we take you all the way to a formal report.

[ Download pdf ]

Strand was founded in 2000 by computer science and mathematics professors from India's prestigious Indian Institute of Science who recognized the need to automate and integrate life science data analysis through an algorithmic and computational approach. Strand's segue into the life sciences was through informatics products and services for research biologists, chemists, and toxicologists that combine advanced visualization, predictive systems modeling, data integration and scientific content management - over 2000 research laboratories worldwide (about 30% of global market share) are licensees of Strand's technology products, including leading pharmaceutical and biotechnology companies, research hospitals and academic institutions. With a recent investment by Biomark Capital, Strand has grown its established team to over 200 employees, many with multidisciplinary backgrounds that transcend computation and biology.

Since 2012, Strand has been expanding its focus to include clinical genomics, spanning sequencing, data interpretation, reporting and counseling. Strand operates a 10,000 square foot laboratory space with state of the art clinical genomics capabilities and is also establishing Strand Centers for Genomics and Personalized Medicine in several hospitals around the world to serve as outreach points for genomic counseling. Based on the experience gained from sequencing, analyzing, interpreting and reporting on clinical samples over a wide variety of clinical indications, Strand has developed an end-to-end solution for clinical labs that handles all stages from analysis to reporting. The interpretation and reporting software platform has been designed and developed specifically for the medical professional, ranging from the molecular pathologist to the physician. By enhancing sequence-based diagnostics and clinical genomic data interpretation using a strong foundation of computational, scientific, and medical expertise, Strand is bringing individualized medicine to the world.

For more information about Strand, please visit www.strandls.com,
or follow us on twitter @StrandLife.