If you are interested in participating in our Early Access Program, sign up here
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Phone (USA): 1-800-516-5181
Phone (Worldwide): +1-650-288-4559
StrandOmics is HIPAA Compliant: View report
We designed Strandomics after extensive interactions with practicing clinicans, patients, clinical interpreters, genetic counselors, and medical geneticists. Strandomics has now been used for analysis and reporting on many many cases, drawn from a growing list of more than 50 hospitals, including world renowned specialist centers in cancer, cardiology and ophthalmology as well as leading community hospitals (a few examples below). Several leading centers in the US are now using Strandomics as part of the Early Access Program.
Strand Centers, our clinical testing arm has used our platform in more than a hundred cases, and has touched many lives with the platform.A few examples:
Widely adopted Algorithms for Alignment and Variant Calling
Our variant detection algorithms have been used extensively in clinical applications.
For instance, click here to see how Wafergen Biosystem used our variant identification algorithms to validate their clinical assays.
And click here to see how the Sanford-Burnham institute used our variant identification algorithms to find the cause of a very rare disorder called CHIME disease.
And click here to see how a team of scientists from various Japanese medical schools used our variant detection algorithms to find a novel gene candidate for Andersen-Tawil syndrome.
And click here to see how the New York City Office of Chief Medical Examiner used our variant detection algorithms to study the cause of sudden unexplained death in a cohort of 274 individuals.
White papers that benchmarks our Alignment and Variant Calling algorithms with leading open source algorithms and show how our algorithms provide greater accuracy are available.
The following statistic gathered in over a hundred cases says it all. When a clinically significant pathogenic, likely pathogenic or strong VUS exists, we usually find it in under 5min using our simple point-and-click interface.
If you'd like to scale up this process, we support capture of comments and role-based access to enable reviews. And we support systematic SOPs to ensure consistency of comments. And we take you all the way to a formal report.
Strand was founded in 2000 by computer science and mathematics professors from India's prestigious Indian Institute of Science who recognized the need to automate and integrate life science data analysis through an algorithmic and computational approach. Strand's segue into the life sciences was through informatics products and services for research biologists, chemists, and toxicologists that combine advanced visualization, predictive systems modeling, data integration and scientific content management - over 2000 research laboratories worldwide (about 30% of global market share) are licensees of Strand's technology products, including leading pharmaceutical and biotechnology companies, research hospitals and academic institutions. With a recent investment by Biomark Capital, Strand has grown its established team to over 200 employees, many with multidisciplinary backgrounds that transcend computation and biology.
Since 2012, Strand has been expanding its focus to include clinical genomics, spanning sequencing, data interpretation, reporting and counseling. Strand operates a 10,000 square foot laboratory space with state of the art clinical genomics capabilities and is also establishing Strand Centers for Genomics and Personalized Medicine in several hospitals around the world to serve as outreach points for genomic counseling. Based on the experience gained from sequencing, analyzing, interpreting and reporting on clinical samples over a wide variety of clinical indications, Strand has developed an end-to-end solution for clinical labs that handles all stages from analysis to reporting. The interpretation and reporting software platform has been designed and developed specifically for the medical professional, ranging from the molecular pathologist to the physician. By enhancing sequence-based diagnostics and clinical genomic data interpretation using a strong foundation of computational, scientific, and medical expertise, Strand is bringing individualized medicine to the world.
For more information about Strand, please visit www.strandls.com,
or follow us on twitter @StrandLife.
The StrandOmics Early Access Program is an invitation only program open to academic and commercial clinical genomics labs that conduct laboratory derived sequencing tests (diagnostic gene panels), whole exome sequencing, and/or whole genome sequencing and deliver results to doctors and patients.X
We strive to provide up-to-date variant content, from both public sources (ClinVar) and proprietary sources: HGMD (needs a license from Biobase) and Strand's own deeply curated database Strand VarDB. The number of variant-publication reports in each database is indicated below.
|Source||Number of Variant-|
|Strand Curated DB||39,597|
The Strand VarDB database is deeply curated around genes commonly tested for cardiology, ophthalmology and germline cancers, in particular around genes offered by the Strand Center tests. Deep curation captures phenotypes and other evidence implicating the variant as shown in the example below, thus enabling faster assessment of variant pathogenicity. This deep curation is facilitated by our Natural Language Processing platform Grammatica, followed by expert curation by a large team of about 50 literature curators and clinical interpreters who have assessed variants in hundreds of tests run by the Strand Center.
This variant was observed in individuals with an age of onset of 9 years. In addition, individuals carrying this variant manifested one or more of the following phenotypes: bilateral central visual loss with beaten metal ellipticalfovealdystrophy and temporal pallor of the optic discs, documented by retinal color photography, with or without yellow-pigment epithelial fluorescein angiographic feature of a dark choroid.
Disease Implication : Possibly implicated (Pathogenic)
|Affected(with Variant)||   ||Normal(with Variant)|